Effect of acidification on biological proprieties of sodium carboxymethylcellulose

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Lamia Mansouri
Meriem Elkolli
Bouanane Zohra


Sodium Carboxymethylcellulose (NaCMC) was subjected to an acidification reaction by hydrochloric acid. Characterization and identification of acidified carboxymethylcellulose (HCMC) was made by Fourier transformed Infrared spectroscopy (FT-IR), Elemental analysis (XRF) and Thermal analysis (TGA - DSC). The opacity measurement shows a marked difference in powders structure. The blood-clotting tests demonstrate that HCMC is more hemostatic than NaCMC. Mucoadhesion exhibits a pronounced increase in adhesion times of HCMC contrary to NaCMC on the gastric and intestinal mucosa. Besides, biodegradability is established.

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Mansouri, L., Elkolli, M., & Zohra, B. (2020). Effect of acidification on biological proprieties of sodium carboxymethylcellulose. Materials and Biomaterials Science, 3(2), 065–070. Retrieved from https://mbmscience.com/index.php/mbms/article/view/33
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